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About NanoVation Therapeutics
NanoVation Therapeutics (NTx) is a gene therapy company developing next-generation platform technologies based on lipid nanoparticles for the safe and efficient delivery of nucleic acids. NTx`s one-stop-shop IP portfolio is utilized to tune formulations to specific applications as well as a variety of tissues. Focused on translating personalized nucleic acid therapies to the clinic, NTx aims to treat and prevent multiple diseases enabling a healthier tomorrow, TODAY.
We are building our team and looking for highly motivated individuals seeking to use their knowledge to revolutionize the healthcare of tomorrow.
Career Opportunity – Scientist or Senior Scientist, RNA
NanoVation Therapeutics (NTx) is looking for an innovative and collaborative Scientist / Senior Scientist RNA to join our team.
Reporting to the Director, RNA, the Scientist / Senior Scientist, RNA will work closely with the RNA Team and will be responsible for designing, executing, analyzing, and making recommendations on our research protocols related to internal and client-based projects, and subsequent data analysis.
Our ideal candidate thrives on contributing collaboratively in a fast-paced, innovative environment and is open and interested in learning a variety of different research techniques.
Some of the ways you will contribute:
Actively contributing to and supporting our core values = Think Big. Innovate. ACT = Innovation, Accountability, Collaboration, Trust.
RNA Research
- Mentors, and executes RNA research in support of our research goals and plans; internal and external projects.
- Independently executes and troubleshoots new RNA capabilities based on RNA group discussions, precedent literature and supervisor input.
- Independently performs experiments and conducts activities in support of nucleic acid design, production, and analysis for quality and activity using required techniques.
- Produces RNA and other related products in support of the formulation, and preclinical teams.
- Determines the purity and identity of synthesized RNA through characterization using state-of-the-art methods, including, but not limited to, analytical-HPLC/MS or preparative-HPLC, RNA gels, capping efficiency, dsRNA levels, endotoxin, RiboGreen assay and/or nanodrop quantitation.
- Assesses mRNA translation performance in vitro and in cells using established cell-free translation assays (CFT) and validated mammalian cell line transfection methods, respectively.
- Coordinates with the Formulation and Preclinical Teams the assessment of RNA activity.
- Follows SOPs; generates and maintains thorough and accurate documentation.
- Generates, analyzes, and tabulates data and results; writes/reviews reports and makes recommendations.
- Meets established deadlines.
- Openly communicates challenges and proposes solutions.
Project Teamwork
- Leads and helps guide project teamwork.
- Provides oversight and technical support to other project teams.
- Prepares and executes multiple internal and external project plans.
- Prepares and reviews study reports and technical presentations for internal use and for clients.
- Proactively collaborates and interacts with partners, and other groups/departments in the organization on related projects to develop, characterize, and test formulations.
Innovation
- Proactively conducts relevant scientific literature searches.
- Fosters scientific discussions with team members to support critical analysis of literature and generated data.
- Actively establishes new capabilities based on literature review.
- Identifies novel research opportunities.
- Assists in the writing of patent applications.
- Develops patentable ideas.
Mentor and Supervise Team Members
- Develops the scientific team through mentorship, supervising, and providing guidance.
- Supports and encourages the personal and professional growth and development of team members.
What you bring and build upon as a member of our team
- PhD in Biochemistry or Molecular Biology and 5+ years of related progressive scientific experience, or the equivalent education and experience.
- Expert theoretical and practical knowledge in key RNA technologies for the design, synthesis, purification and quantification RNA. Firm understanding of most biochemical and biophysical techniques that include structural biology, nucleotide chemistry, physicochemical properties of RNA and analytical techniques.
- Expert knowledge in areas of RNA Biology, including transcription, RNA processing and transport, translation, mechanisms of transcriptional/translational control, RNA decay and associated mechanisms, and RNA protein-interaction.
- Demonstrated leadership in positively leading and mentoring less experienced team members.
- Demonstrated leadership in the management of multiple research projects and budgets.
- Strong organizational skills, time management, and ability to prioritize.
- Established track record of innovation and contribution of novel ideas.
- Strong communication skills both written and oral: Communicates with respectful, honest, open, and objective communication.
- Strong Initiative: Proactively looks for opportunities for self, peers, and the company.
- Innovative: Proactively learns, adapts, and generates new ideas individually and as a team member.
- Solution Oriented: Proactively looks for solutions and comes to the table with assessments and solutions for self, peers, and the company.
- Flexibility: Proactively plans ahead and is open to a variety of options and embraces change.
- Lifelong Learner: Continuous learning and sharing of knowledge. Being curiosity-driven; looks for and finds the answers, collaboratively.
What we offer
This full-time role will be located at 2405 Wesbrook Mall, Vancouver, BC V6T 1Z3, Canada
Your compensation package will include many components including:
- Salary range $70,000 – $110,000 per year (Your employment offer will be determined based on many factors including, but not limited to the level of role you are hired for and internal and external equity)
- Employee benefits medical, dental, life insurance, ADD, EAP
- Bonus eligibility
- Generous vacation time
- Company Stock Options
- Annual professional development budget
How to Apply
To submit your application, please apply through our career portal. We would like to thank all applicants who apply. Please note that only those selected for an interview will be contacted.
All qualified applicants will receive consideration for employment without regard to race, colour, ancestry, place of origin, religion, marital status, family status, physical or mental disability, sex, sexual orientation, gender identity or expression, or age.
